RISK FACTORS OF CHD ΙΝ SCHOOL CHILDREN WITH POSITIVE FAMILY HISTORY
Abstract
This is a comparative study of the risk factors in coronary heart disease (CHD) between children whose parents have a positive family history of CHD and children without a positive family history of CHD. 350 thirteen-year-old scholars answered with the help of their parents to a special questionnaire. 133 of the students, after a written consent, had a blood analysis of the following parameters. Blood glucose, total colesterol LDL, HDL, triglycerides, fibrinogen and plasma viscosity. The determination of the plasma viscosity was measured at 25° C with a capillary viscosimeter LUCKHAM. From the total of the 133 children whose blood was tested, the 23 (6.04%) had a positive family heredity of CHD. The P-Viscosity levels although higher in the positive group did not differ significantly (Ρ 0,912). Furthermore, we could not establish any differences in the fibrinogen and arterial pressure measurements.References
Neufeld HN and Goldhourt V: Coronary heart disease: Genetic aspects Circulation. 1983; 67: 943.
Feinleib Μ: Genetics: Preνention of Coronary Heart disease, Practical Management of the Risk Factors Philadelphia W.B. Saunders Company, 1983.
Conroy RM, Mulcahy R, Hickey Naud Daly L: Has family history of coronary heart disease an independent coronary risk factor; Br Heart J. 1983; 53: 378.
Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990 s. Natura, 1993. 1993; 362: 801-09.
Study Group, European Arherosclerosis Society. Strategy for prevention of coronary heart diseases: Α policy statement of the European Atherosclerosis Society. Eur. Heart J. 1987; 8: 77-78.
Preνention of coronary heart disease in clinical practice. Recommendation of the Task Force of the European Society of Cardiology. Eur Heart J. 1994; 15: 1300-34.
Webber LS, Voors ΑW, Srinivasan SR, Frerichs RR, Berenson GS. Occurence in children of multiple risk factors for coronary artery disease. The Bogalusa Heart Study. Pren Med 1979; 8: 407-18.
Ernst ND, Obarrzanek Ε. Child Health and Nutrition: Obesity and High Blood Cholesterol. Preventive Medicine. 1994; 23: 427-36.
Aravanis C, Mensink RP, Karalias Ν, Christodoulou B, Kajatos Α, Katau ΜΒ. Serum lipids, apoproteins and nutrient intate in rural cretan boys consuming high-olive-oil diets. Journal of Cl Epidemiology 41. 1998; 11: 1117-23.
Pindus G, Sen C, Wentel Ε, Jung F. Modern Strategies for treatment οf acute myocardial infarction: Significance οf haemostaseological and rheological findings Adv Exp Med Biol. 1990; 281: 389-94.
Εrnst Ε, Kranth V, Resch KL. Panlsen HF. Does blood rheology revent to normal after myocardial infarction? Βr Heart J. 1990; 64: 248-50.
Kushner I. The phenomenon of the acute phase response Ann NY Acad Sci. 1992; 389: 39-48.
Chien S, Dormandy J, Εrnst Ε, Matrai Α. Clinical Hemorheology. Marthinus, Ni; hoff Publishers. Boston 1987.