A REPORT ΟΝ ΤΗΕ RADIOSENSITIZATION PRQPERTIES OF LOW-DOSE cDDP (CIS-DIAMMINE-DICHLOROPLATINUM II - CISPLATINUM) ΙΝ ΤΗΕ MANAGEMENT OF ΤΗΕ VERY ADVANCED CARCINOMA OF ΤΗΕ VULVA

Authors

  • Γ. ΜΑΝΩΛΑΚΗΣ
  • Κ. ΚΥΠΡΙΑΝΟΥ
  • Γ. ΚΟΛΙΤΣΗ
  • Γ. ΤΣΑΚΑΛΟΣ
  • Π. ΑΝΑΣΤΑΣΙΑΔΗΣ
  • J.A. PACELLA

Abstract

Eight patients, eligible for evaluation, with very advanced (Stage III & ΙV) poorly differentiated squamous cell carcinoma οf the vulva were subjected to a pilot-protocol involving sub-therapeutic levels of both radiation and cDDP concurrently. Local control as well as palliation were achieved in most cases. The radiosensitization properties of low-dose cDDP are raised in this pilot study. Entrance criteria were inoperability of post operative recurrence.

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